The manuscript describing our new phylogenetically inspired approach to modeling epigenetic dynamics just appeared in Bioinformatics:
Modeling DNA methylation dynamics with approaches from phylogenetics
You can download an R package that implements our models here.
Farewell to our undergrad interns Laura Colbran and Vir Patel. It was a great pleasure having them work with us this summer.
The manuscript describing EnhancerFinder, our integrative machine learning approach to predicting gene regulatory enhancers genome-wide, just appeared in PLOS Computational Biology:
Integrating Diverse Datasets Improves Developmental Enhancer Prediction
Our predictions are available in a track hub for the UCSC Genome Browser. Follow that link and then click on the “My Hubs” tab to access them. Check out the paper for details.
Tony just returned from co-organizing a symposium called “How Old is my Gene? Large scale analysis of gene age and function” at the annual Society for Molecular Biology and Evolution meeting in San Juan, Puerto Rico.
Check out the preprint describing our new approach to modeling DNA methylation dynamics:
Modeling DNA methylation dynamics with approaches from phylogenetics
[arXiv] (Joint work with Dennis Kostka)
Our work on human-specific enhancers of gene expression was recently featured in the Vanderbilt University Reporter!
Update: Our work was also highlighted in ScienceDaily: Fast-Mutating DNA Sequences Shape Early Development; Guided Evolution of Uniquely Human Traits!
Our paper Many human accelerated regions are developmental enhancers was just published in Philosophical Transactions of the Royal Society B.
Check out the press release.
Our work was recently featured in the Vanderbilt Reporter’s Pioneers of Discovery series.
Several good things have happened to members of the Capra Lab recently. A few highlights:
Tony gave invited seminars at the Université de Montréal, the University of Kentucky, and the University of Virginia.
Corinne Simonti presented her poster “Examining Disease SNPs for regulatory enhancer potential: What does a non-coding GWAS hit really mean?” at ASHG 2013.
Mike Sivley won a poster prize at the 2013 CHGR Symposium.
Tony helped to organize and spoke at the 2013 CHGR Symposium.
Welcome to the new Capra Lab Website! We have migrated to WordPress to make it easier to share news and update the site.